Sage (Salvia Officinalis) ameliorates experimentally induced neurodegeneration in C. elegans
نویسندگان
چکیده
منابع مشابه
Antioxidative Phenolic Compounds from Sage (Salvia officinalis)
Ten phenolic compounds were isolated from a butanol fraction of sage extracts. Their structures were determined by spectral methods (NMR, MS, IR). Among them, a novel compound, 4-hydroxyacetophenone-4-O-â-D-apiofuranosyl-(1f6)-O-â-D-glucopyranoside, was identified. Two test systems, DPPH free radical scavenging activity and radical cation ABTS•+ scavenging activity, were used to evaluate their ...
متن کاملChemical and genetic relationships among sage ( Salvia officinalis L.) cultivars and Judean sage ( Salvia judaica Boiss.).
The essential oil composition and genetic variability of common sage ( Salvia officinalis L.) and its three ornamental cultivars ('Purpurascens', 'Tricolor', and 'Kew Gold') as well as Judean sage ( Salvia judaica Boiss.) were analyzed by GC-FID, GC-MS, and random amplified polymorphic DNA (RAPD). Common sage and its cultivars contained the same volatile compounds; only the ratio of compounds d...
متن کاملPhytochemical Study and Biological Activity of Sage (Salvia officinalis L.)
This study presents an attempt to evaluate the antioxidant potential and antimicrobial activity of methanolic extract, and essential oils prepared from the leaves of sage (Salvia officinalis L.). The content of polyphenol in the methanolic extracts from the leaves of Salvia officinalis was determined spectrophotometrically, calculated as gallic acid and catechin equivalent. The essential oils a...
متن کاملMetal-induced neurodegeneration in C. elegans
The model species, Caenorhabditis elegans, has been used as a tool to probe for mechanisms underlying numerous neurodegenerative diseases. This use has been exploited to study neurodegeneration induced by metals. The allure of the nematode comes from the ease of genetic manipulation, the ability to fluorescently label neuronal subtypes, and the relative simplicity of the nervous system. Notably...
متن کاملMetformin-like effect of Salvia officinalis (common sage): is it useful in diabetes prevention?
Common sage (Salvia officinalis L.) is among the plants that are claimed to be beneficial to diabetic patients, and previous studies have suggested that some of its extracts have hypoglycaemic effects in normal and diabetic animals. In the present study, we aimed to verify the antidiabetic effects of an infusion (tea) of common sage, which is the most common form of this plant consumed. Replaci...
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ژورنال
عنوان ژورنال: The FASEB Journal
سال: 2012
ISSN: 0892-6638,1530-6860
DOI: 10.1096/fasebj.26.1_supplement.1025.10